Glucosylceramides of pig epidermis: structure determination.
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چکیده
منابع مشابه
Glucosylceramides of pig epidermis: structure determination.
Six series of glucosylceramides from pig epidermis have been identified, and their structures have been determined. The structural types identified are: 1, N-acylglucosylsphingosines (33%); 2, N-acylglucosylphytosphingosines (13%); 3, N-(omega-hydroxyacyl)-glucosylsphingosines (3%); 4, N-(alpha-hydroxyacyl)-glucosylphingosines (15%); 5, N-(alpha-hydroxyacyl)-glucosylsphingosines (16%); 6, N-(al...
متن کاملAcylglucosylceramides of pig epidermis: structure determination.
The acylglucosylceramides of pig epidermis comprise 56% of the total glucosylceramides and 3.3% of the total epidermal lipid by weight. Contrary to an earlier report on this lipid, the amide-linked fatty acid is not a dihydroxypentatriacontadienoic acid; rather, the fatty acids are a series of long chain omega-hydroxy acids consisting of 58% saturates, 35% monoenes, and 7% dienes, with predomin...
متن کاملLinoleate-rich acylglucosylceramides of pig epidermis: structure determination by proton magnetic resonance.
The structure of the linoleate-rich acylglycosylceramides isolated from pig epidermis has been reinvestigated. Gas-liquid chromatographic analysis of the alditol acetates produced from the sugar component indicated that 90% of the hexose is glucose while the remaining 10% is galactose. The predominance of the beta-D-glucosyl group was confirmed by 360 MHz proton magnetic resonance spectroscopy....
متن کاملIsolation and characterization of plasma-membrane glycoproteins from pig epidermis.
1. Non-desmosomal plasma membranes enriched in plasma-membrane marker enzymes and in metabolically labelled glycoproteins were isolated on a large scale from up to 500g of pig ear skin slices. Sodium dodecyl sulphate/polyacrylamide-gel electrophoresis and periodic acid/Schiff staining revealed the presence of four major glycosylated components in the apparent molecular-weight range 150000-80000...
متن کاملGlucosylceramides stimulate murine epidermal hyperproliferation.
Hydrolysis of glucosylceramides (GlcCer) by beta-glucocerebrosidase generates ceramides, critical components of the epidermal permeability barrier. Ceramides also are involved in the regulation of cellular proliferation and differentiation in a variety of cell types. Whereas most studies have focused on ceramides and their sphingoid base metabolites as growth inhibitors, GlcCer apparently acts ...
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ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 1983
ISSN: 0022-2275
DOI: 10.1016/s0022-2275(20)37896-2